Susmita Dey, MS Scholar
Education
M.S in Bioengineering in CMC, Vellore(2015-2017).
BTech in Biomedical Engineering, JIS College of Engineering(2011-2015)
BTech in Biomedical Engineering, JIS College of Engineering(2011-2015)
Research interests
Scaffold Biomimetic for tissue engineering, Medical Imaging, Artificial Organs.
Projects
Masters Thesis: Assessment of blood flow changes in the plantar foot of patients with Diabetes Mellitus 2
Plantar ulcers and lower-limb amputations among individuals with diabetes mellitus (DM) contribute towards the morbidity and mortality caused by this disease. Foot ulceration affects some patients with DM. A classical triad of neuropathy, ischemia, and infection characterizes this foot ulceration and due to the impaired metabolic mechanisms in DM; there are increased risk of infection and poor wound healing due to a series of mechanisms, one of those being diminished peripheral blood flow and decreased local angiogenesis finally leading to tissue necrosis and gradually to amputation.
Apart from the associated complications, it also hinders the quality of the life, leading to an increased risk of infection and poor wound healing. Insensate limbs are often prone to injury and their movements are hindered as it alters the anatomical framework of the foot leading to formation of deformities, which in turn create abnormal bony prominences and pressure points predisposing to ulcers. Traditionally one assessment involves looking into early microvascular changes. The displacement of metatarsal fat pads distally reduces the cushioning effects of the metatarsal heads causing increase in the pressure points and resulting in callus formation causing skin breakdown and ulceration; blood flow patterns in these pressure points are affected.
Early identification of risk factors for ulceration is necessary to prevent injuries to the feet of these subjects. High plantar pressure, combined with insensitivity, is a proven risk factor for ulceration among these patients, and is the presently used evaluation test for this purpose. Evaluation of blood flow will provide additional information to identify areas with such propensities.
The design will use plethysmography sensors to record the Photo plethysmography data. The data collection for the study will be done by using the wearable reflectance type plethysmograph sensors, which unlike the conventional Photo plethysmography sensors does not use the IR or red wavelength but uses the green wavelength.
Plantar ulcers and lower-limb amputations among individuals with diabetes mellitus (DM) contribute towards the morbidity and mortality caused by this disease. Foot ulceration affects some patients with DM. A classical triad of neuropathy, ischemia, and infection characterizes this foot ulceration and due to the impaired metabolic mechanisms in DM; there are increased risk of infection and poor wound healing due to a series of mechanisms, one of those being diminished peripheral blood flow and decreased local angiogenesis finally leading to tissue necrosis and gradually to amputation.
Apart from the associated complications, it also hinders the quality of the life, leading to an increased risk of infection and poor wound healing. Insensate limbs are often prone to injury and their movements are hindered as it alters the anatomical framework of the foot leading to formation of deformities, which in turn create abnormal bony prominences and pressure points predisposing to ulcers. Traditionally one assessment involves looking into early microvascular changes. The displacement of metatarsal fat pads distally reduces the cushioning effects of the metatarsal heads causing increase in the pressure points and resulting in callus formation causing skin breakdown and ulceration; blood flow patterns in these pressure points are affected.
Early identification of risk factors for ulceration is necessary to prevent injuries to the feet of these subjects. High plantar pressure, combined with insensitivity, is a proven risk factor for ulceration among these patients, and is the presently used evaluation test for this purpose. Evaluation of blood flow will provide additional information to identify areas with such propensities.
The design will use plethysmography sensors to record the Photo plethysmography data. The data collection for the study will be done by using the wearable reflectance type plethysmograph sensors, which unlike the conventional Photo plethysmography sensors does not use the IR or red wavelength but uses the green wavelength.